Ulcers are tissue defects that can occur on the surface of the skin or mucous membranes. They are damaged or dead areas that can arise from a variety of causes, such as trauma, inadequate blood supply, infection, systemic disease or chronic pressure on an area of the body. Non-healing wounds are wounds that have difficulty in the healing process. They can occur for a variety of reasons, including infection, reduced ability of the body to regenerate tissue, poor wound management, chronic inflammation or the presence of risk factors such as diabetes or nutritional deficiencies. Ulcers and non-healing wounds are a significant health problem because they are prone to infection, can lead to serious complications and can significantly affect patients' quality of life. Their treatment can involve a variety of strategies, such as the use of dressings, antibiotics, surgical removal of dead tissue, and treatment of the underlying cause that contributed to the ulceration or non-healing wound.